1.work in通常指在什么地方工作(工作单位的规模较大)；强调里面、内部。2.work at从事某事，或者是致力于某种工作，也可以指在小规模的地方工作；强调大概地点。
work at双语例句
1、She has to work at weekends from time to time.
她偶尔周末还得工作。
2、It's very difficult to find work at the moment.
目前很难找到工作。
3、I go to work at 8 o'clock.
我8点钟去上班。
work in双语例句
1、All I know is that she used to work in a bank.
我只知道她曾在银行工作过。
2、It is difficult to find work in the present economic climate.
在目前这种经济大气候下很难找到工作。
3、I got to work in record time.
我以历来最快的速度赶到单位上班